Traditional is as simple as grabbing your pen and going over your lines. Of course, we need to probably go into a little more than just basic pens. You're going to want to look into art pens like Micron pens. There's also the option of using a quill tip to work with.
If you want to go for very dynamic lines that pop on their own and have a really cool style, mastering the quill is a great method. Quills can create some absolutely stunning artwork.

A quill pen can create very dynamic lines.
If you work with Micron pens though, you may have a decent shot of imitating the style of a quill without the hassle. You can press harder to make the micron pens thicken their line. Also, you can get several tip sizes to begin with. It should only be noted that very thin pens like .05mm don't get thicker, they usually only will get ruined.

Micron pens are pressure sensitive.
You want to finish your line work up and then use an eraser to take up your pencil lines. All that will be left will be the clean ink, assuming you didn't draw too darkly with your pencil marks and have areas that won't come up. If that's the case, no worries you can always clean things up in Photoshop a bit.
So it's type to get out the scanner and scan your artwork. Don't forget if you plan to use your art professionally to at least scan at 300 DPI. Next we'll work on cleaning up the art.
Cleaning up with "Levels"
To clean up any smudges and lines left on your paper, start by opening up the levels menu. To do so, go to the menu bar at the top and navigate to Image>Adjustments>Levels... Alternatively, you can use the shortcut command of Shift+L

How to get to the levels command.
Your basic input levels should be 0, 1.0, and 255. These are the shadows, midtones, and highlights respectively. The easiest way to use them is to drag the corresponding arrows below the number values.

The levels toolbox
Dragging the left shadows slider, brings out all the darks, not messing with the lights. Of course, you will have some areas that have a tiny bit of darkness that will become clearer, such as smudges on the page. To fix that, you'll mess with the highlights (the right white) and the midtones (the center) sliders.

Using the shadows slider to darken the line-art.
For the most part, dragging the highlights slider towards the center a bit will be enough to remove the smudges and extra lines from your paper. The only reason you may need the midtones slider is if using the highlights slider starts to mess up any of your actual lines. You can mess with all 3 to get the best overall look for your artwork.

Bring out the highlights.
Cleaning up with the Dodge Tool.
Alternatively, you can use the dodge tool from the tool bar. If either the burn tool or the sponge tool are active in the slot, you'll have to click and hold on the spot until the little menu opens up to let you select the dodge tool.

The dodge tool...
If you take the dodge tool and set it's settings (at the top under the menu bar) to "Highlights" you can easily get rid of smudges and marks. This can be used in conjunction with the Levels menu above to finish cleaning up areas that were not easily removed already.

The dodge tool cleaning up the remains...
Desaturate
The only other thing you may want to consider is desaturating your linework, if it scanned and had too much of a tint like a purple or blue color to it. (A lot of pencil work in particular can come across purplish when scanned on cheap scanners.) To quickly desaturate an image, go to in the top menu bar to Image>Adjustments>Hue/Saturation... or use the shortcut command of ctrl+u.

Notice the subtle change when the linework is desaturated.
You can there drag the saturation bar to the left. Taking it all the way to -100 is full desaturation, and anywhere in between desaturates it by that much percent. |